WebTelaprevir (Incivek) is a NS3/4A hepatitis C protease inhibitor. Specifically, telaprevir inhibits the proteolytic cleavage of the HCV encoded polyprotein, an essential step in the viral life … WebIncivek is a substrate of CYP3A and P-gp; therefore, drugs that induce CYP3A and/or P-gp may decrease Incivek plasma concentrations and reduce the therapeutic effect of …
Diagnosis and Management of Hepatitis C AAFP
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Side Effects of Incivek (telaprevir): Interactions & Warnings
WebThe most frequent serious adverse events in subjects treated with Incivek combination treatment were: skin disorders (rash and/or pruritus) and anemia. Fourteen percent of subjects discontinued Incivek due to adverse drug reactions. The following were the most frequent adverse drug reactions leading to discontinuation of Incivekrash: anemia, WebMay 24, 2011 · Incivek's side effects include rashes and anemia, the FDA said. The rash can be serious and can require stopping the drug. Incivek is poised to nearly doubling the chances of curing the serious ... WebFor serious skin reactions, including rash with systemic symptoms or a progressive severe rash, INCIVEK, peginterferon alfa, and ribavirin must be discontinued immediately. Discontinuing other medications known to be associated with serious skin reactions should be considered. ... If ribavirin is permanently discontinued for the management of ... crystal stairs provider payment