WebOne of the more intriguing aspects of cytochrome P450 is the enzyme's use of a thiolate-ligated heme to perform demanding two-electron oxidations. This coordination is unusual, given that thiolate ligation can significantly decrease a heme reduction potential. Web7 apr. 2009 · X-ray crystallographic analysis confirms that replacing the heme–thiolate with a heme–selenolate constitutes a highly conservative substitution. Despite the slightly larger van der Waals radius of selenium compared with sulfur, the geometry and environment of the heme ligand are fully preserved in the mutant.
Category:Heme-thiolate proteins - Wikipedia
WebEleven years ago, a secreted heme-thiolate peroxidase with promiscuity for oxygen transfer reactions was discovered in the basidiomycetous fungus, Agrocybe aegerita. … Web21 mrt. 2012 · Probable heme-thiolate monooxygenase. By similarity Caution Reported as CYP749A22 in the publication but submitted as CYP749A20. Cofactor Protein has 1 cofactor binding site: heme ( UniProtKB Rhea CHEBI:30413 ) By similarity Features Showing features for binding site. Expand table GO annotations Expand table Complete … canned toys
Probing the role of the proximal heme ligand in cytochrome
Web25 feb. 2011 · Synthesis, Structure, and Reactivity of Biomimetic Catalysts Modeling Non-Heme and Non-Corrinoid Thiolate Ligated Iron and … Web16 okt. 2015 · The gene of A. aegerita peroxygenase (apo1) was identified on the level of messenger RNA and genomic DNA and peptide sequences obtained through an Edman … fix remote firewall