WebMar 15, 2013 · Daptomycin is a concentration-dependent bactericidal agent currently approved at 4 and 6 mg/kg of body weight daily for the ... gender, weight, and renal function), infection site, diagnosis, severity of illness at the initiation of high-dose daptomycin therapy as determined by APACHE II score, comorbid conditions, prior and … WebDaptomycin is a lipopeptide antibiotic active against gram-positive organisms and recently approved for marketing in Japan. This study investigates the efficacy and safety of daptomycin in Japanese patients with skin and soft tissue infections (SSTIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) for regulatory filing in Japan.
Daptomycin - GlobalRPH
WebMar 18, 2024 · Several reports have suggested a role for Corynebacterium striatum as an opportunistic pathogen. The authors have conducted a retrospective study at the Clinical Center of the University of Szeged, Hungary, between 2012 and 2024 that revealed significantly increased rifampicin resistance in this species. This work aimed to … WebMar 1, 2024 · Daptomycin injection is used to treat complicated skin and skin structure infections (cSSSI). It is also used to treat infections in the bloodstream (bacteremia), … fish oil manufacturing process
Daptomycin-Rifampin-Induced Rhabdomyolysis, Acute Renal …
WebApr 2, 2024 · Vancomycin (VCM) and daptomycin (DAP) are standard therapies for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, despite concerns regarding clinical utility and growing resistance. Linezolid (LZD) affords superior tissue penetration to VCM or DAP and has been successfully used as salvage therapy for persistent MRSA … WebNov 23, 2024 · Uses: For the treatment of patients with S aureus bloodstream infections (bacteremia), including those with right-sided infective endocarditis, due to methicillin-susceptible and methicillin-resistant isolates Usual Pediatric Dose for Skin and Structure Infection 1 to less than 2 years: 10 mg/kg IV every 24 hours WebThe risk of nephrotoxicity and complications necessitates the need for dose titration in the special population with impaired renal function. 54 Clindamycin, active against MRSA, has good tissue penetration (97%) and tolerability profile, and the ability to inhibit production of bacterial toxins common in CA-MRSA infection. 27 However ... fish oil lower triglycerides