Circrhot1
WebFigure 1. CircRHOT1 is enhanced in clinical NSCLC samples and NSCLC cell lines. (A) The expression of circRHOT1 was analyzed by qPCR in clinical NSCLC tissues (n = 60) and peri-tumor tissues (n = 60).(B) The expression of circRHOT1 was measured by qPCR in the indicated cells.(C) The back-spliced and canonical forms of RHOT1 expression was … WebJan 21, 2024 · CircRHOT1 knockout, by depleting flanking CSs, was shown to suppress HCC’s cell proliferation . Knockdown of circRHOT1 via Cas13d in two HCC cell lines, Huh7 and PLC/PRF/5, inhibited cell proliferation (Fig. 3i, j). CircHIPK3 is another circRNA that is known to promote proliferation of the colon cancer cell line HCT116 .
Circrhot1
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WebMar 3, 2024 · CircRHOT1 promotes proliferation and inhibits apoptosis of breast cancer cells. (A) The MDA-MB-231 cells were treated with control shRNA or circRHOT1 shRNA. The expression of circRHOT1 was measured by qPCR in the cells. (B–G) The MDA-MB-231 and T47D cells were treated with control shRNA or circRHOT1 shRNA. WebAug 18, 2024 · CircRHOT1 is involved in the modulation of cell invasion, apoptosis, and proliferation by targeting miR-125a-3p in pancreatic cancer cells [11]. CircRHOT1 is increased and contributes to cell invasion and proliferation of pancreatic cancer cells [12]. Our data showed that circRHOT1 was elevated in clinical NSCLC samples and NSCLC …
WebNational Center for Biotechnology Information WebCircRHOT1 represses autophagy and in the OA rat model. (a)–(e) The OA rat model was constructed by receiving ACLT, and the OA rats were treated with circRHOT1 shRNA. (a) The expression of...
Webnegatively correlated with circRHOT1 and CCND1, and the circRHOT1 expression was positively associated with CCND1 in clinical OA samples. Meanwhile, the apoptosis was induced in OA rats but the depletion of circRHOT1 could block the phenotype in the rats. The articular cartilage degeneration was promoted in OA rats, while the knockdown of … WebcircRHOT1 and TIP60. RNA-sequencing method was used to analyze the downstream target gene of circRHOT1. Results: We identified circRHOT1 (hsa_circRNA_102034) as …
WebThe study by Wang et al 34 showed that circRHOT1 is upregulated in HCC tissues and is associated with a poor prognosis. In-body and out-of-body studies have shown that circRHOT1 triggers the expression of NR2F6 to promote tumor growth and metastasis. The above research shows that circRNA participates in various biological behaviors of HCC, …
Web(a) circRHOT1 level in BC cell lines detected by qRT-PCR. (b, c) circRHOT1 and RHOT1 mRNA expression measured by qRT-PCR in HT-1376 (b) and HTB9 (c) cells treated with … grand junction community center iowaWebKnockdown of circRHOT1 expression significantly inhibited proliferation as well as invasion, and it promoted apoptosis of pancreatic cancer cells via the regulation of E2F3 through the targeting of miR-125a-3p.Conclusion: Taken together, our results demonstrated that circRHOT1 plays critical roles in regulating the biological functions of … grand junction co minimum wageWebDownload scientific diagram circRHOT1 knockout suppresses HCC cell proliferation, migration and invasion but promotes apoptosis. a The expression of circRHOT1 was analyzed by qRT-PCR in ... grand junction colorado theatersWebJun 1, 2024 · CircRHOT1 is a recently spotted circular RNA that is upregulated in several cancers, mainly in hepatocellular carcinoma and pancreatic cancer. (Zhang et al., 2024, … chinese food in america corinna lotharWebMar 3, 2024 · The circRHOT1 knockdown notably increased the levels of reactive oxygen species (ROS), iron, and Fe2+in breast cancer cells. Mechanically, circRHOT1 was able to sponge microRNA-106a-5p (miR-106a-5p) and inhibited ferroptosis by down-regulating miR-106a-5p in breast cancer cells. grand junction co mattress storesWeb4481 Heath Cir, Rohnert Park CA, is a Single Family home that contains 1576 sq ft and was built in 1981.It contains 3 bedrooms and 2 bathrooms.This home last sold for $580,000 in … grand junction colorado map of coloradoWebJul 22, 2024 · CircRHOT1 is overexpressed and affects the biological function of pancreatic cancer cells. A, Relative expression of circRHOT1 in PDAC cells and human pancreatic … grand junction colorado weather by month